ACMSD Polyclonal Antibody

Background:
The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
2 amino 3 carboxymuconate 6 semialdehyde decarboxylase, 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase, acmsd, ACMSD, Aminocarboxymuconate semialdehyde decarboxylase, Picolinate carboxylase

Immunogen: Recombinant protein of human ACMSD

Swissprot: Q8TDX5
Gene Accession: BC016018

Calculated MW: 38 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-107372/sc-107373