Aconitase 2 polyclonal, anti-human, mouse, rat

Background:
Aconitase 2, mitochondrial is a protein that in humans is encoded by the ACO2 gene. The protein encoded by this gene belongs to the aconitase/IPM isomerase family. It is an enzyme that catalyzes the interconversion of citrate to isocitrate via cis-aconitate in the second step of the TCA cycle. This protein is encoded in the nucleus and functions in the mitochondrion. It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15 (PRSS15), also known as Lon protease, after oxidative modification.

Alternative Name:
Aconitase, ACO2, ACO 2, ACO2, ACON, aconitase 2, Aconitase 2 mitochondrial, Aconitase, Aconitase2, Aconitate hydratase, Aconitate hydratase mitochondrial, ACONM, Citrate hydro lyase, Citrate hydro-lyase, ICRD, mitochondrial,

Application Dilution:
WB:1:500-1:2,000
ICC:1:50-1:200
IHC:1:50-1:200
IP:1:10-1:50

Specificity: Aconitase 2 polyclonal antibody detects endogenous levels of Aconitase 2 protein.

Immunogen:
Recombinant protein within human Aconitase 2 aa 1-150.

MW: 85 kDa

Swiss-Prot: Q99798(Human) Q99KI0(Mouse) Q9ER34(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.