ACP6 Polyclonal Antibody

Background:
Lysophosphatidic acid phosphatase type 6 (ACP6), also designated acid phosphatase-like protein 1 (ACPL1) or lysophosphatidic acid phosphatase (LPAP), is a 428 amino acid secreted protein that hydrolyzes lysophosphatidic acid to monoacylglycerol. ACP6 is highly expressed in kidney, heart, small intestine, muscle, liver, prostate, testis, ovary and exists as two isoforms as a result of alternative splicing events. The gene encoding ACP6 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene of human chromosome 1, which encodes lamin A. Stickler syndrome, Parkinsons, Gaucher disease, familial adenomatous polyposis and Usher syndrome are also associated with chromosome 1. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.

Research Area: Metabolism, Signal Transduction

Synonyms:
Acid phosphatase 6, Acid phosphatase 6, lysophosphatidic, Acid phosphatase like 1, Acid phosphatase like protein 1, Acid phosphatase-like protein 1, ACP6, ACPL1, LPAP, Lysophosphatidic acid phosphatase 6, Lysophosphatidic acid phosphatase type 6, Lysophosphatidic acid phosphatase type 6 precursor, lysophosphatidic, PACPL1, PPA6

Immunogen: Recombinant protein of human ACP6

Swissprot: Q9NPH0
Gene Accession: BC034686

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-160126