ACR polyclonal (C-term), anti-human
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In stock
SKU
AC-AP9079b
Catalog Number: AC-AP9079b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB16798
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB16798
Applications: IHC-P, WB
Datasheet
Request Information
Background:
ACR is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.
Other Names:
Acrosin, Acrosin light chain, Acrosin heavy chain, ACR, ACRS
Target/Specificity:
This ACR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-416 amino acids from the C-terminal region of human ACR.
Antigen Region:
387-416
Antigen Type: Synthetic Peptide
Gene Name: ACR
Gene ID: 49
Primary Accession: P10323
NCBI Accession: NP_001088.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
ACR is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.
Other Names:
Acrosin, Acrosin light chain, Acrosin heavy chain, ACR, ACRS
Target/Specificity:
This ACR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-416 amino acids from the C-terminal region of human ACR.
Antigen Region:
387-416
Antigen Type: Synthetic Peptide
Gene Name: ACR
Gene ID: 49
Primary Accession: P10323
NCBI Accession: NP_001088.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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