ACSL3 polyclonal antibody, anti-human, mouse, rat

Background:
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity| subcellular localization| and tissue distribution| all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters| and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain| and preferentially utilizes myristate| arachidonate| and eicosapentaenoate as substrates. The amino acid sequence of this isozyme is 92% identical to that of rat homolog. Two transcript variants encoding the same protein have been found for this gene.

Research Area: Cardiovascular, Metabolism, Signal transduction

Synonyms: Long-chain-fatty-acid--CoA ligase 3 , EC 6.2.1.3, Long-chain acyl-CoA synthetase 3, LACS 3

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year