ACSL5 polyclonal antibody, anti-human, mouse, rat

Background:
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity| subcellular localization| and tissue distribution| all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters| and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen| and in trace amounts in normal brain| but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene.

Research Area: Signal transduction

Synonyms: Long-chain-fatty-acid--CoA ligase 5 , EC 6.2.1.3, Long-chain acyl-CoA synthetase 5, LACS 5

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year