ACSL5 Polyclonal Antibody

Background:
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
ACSL5, ACS2, ACS5, FACL5

Immunogen: Recombinant fusion protein of human ACSL5 (NP_057318.2).

Swissprot: Q9ULC5
Gene ID: 51703

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IHC 1:20-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.