ACTC1 Polyclonal Antibody

Background:
Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).

Research Area: Cardiovascular, Signal Transduction

Synonyms:
ACTC, ACTC, ACTC1, Actin alpha cardiac muscle 1, Actin, alpha cardiac muscle 1, Alpha-cardiac actin, ASD5, CMD1R, CMH11, LVNC4

Immunogen: Fusion protein of human ACTC1

Swissprot: P68032
Gene Accession: BC009978

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.14 mg/mL
Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.