ACTG polyclonal antibody, anti-human, mouse, rat

Background:
Actins are highly conserved proteins that are involved in various types of cell motility| and maintenance of the cytoskeleton. In vertebrates| three main groups of actin isoforms| alpha| beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton| and as mediators of internal cell motility. Actin| gamma 1| encoded by this gene| is a cytoplasmic actin found in non-muscle cells. Mutations in this gene are associated with DFNA20/26| a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss. Alternative splicing results in multiple transcript variants.

Research Area: Signal transduction

Synonyms: Actin, cytoplasmic 2 , Gamma-actin [Cleaved into: Actin, cytoplasmic 2, N-terminally processed]

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year