ACTG1 polyclonal, anti-human, mouse, rat

Background:
Actins are highly conserved proteins that are involved in various types of cell motility, and maintenance of the cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta and gamma have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton, and as mediators of internal cell motility. Actin, gamma 1, encoded by this gene, is a cytoplasmic actin found in non-muscle cells. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss. Alternative splicing results in multiple transcript variants.

Synonyms: ACT, ACTB, ACTG, ACTG1, Actin, cytoplasmic 2, actin, gamma 1, Gamma actin

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human ACTG1

Gene Symbol: ACTG1

Gene ID: 71

Swiss prot: P63261

Calculated MW: 42kDa

Recommended dilution:
WB 1:5000-8000, IHC 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.