Activin A Receptor Type IC (ACVR1C) polyclonal (N-term A48), anti-human
€0.00
In stock
SKU
AC-AP7102a
Catalog Number: AC-AP7102a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB8195
Applications: IHC-P, WB
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB8195
Applications: IHC-P, WB
Datasheet
Request Information
Background:
ACVR1C, a serine/threonine protein kinase, is a type I receptor for the TGFB family of signaling molecules. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors. ACVR1C is a receptor for activin AB, activin B and NODAL. This protein plays a role in cell differentiation, growth arrest and apoptosis.
Other Names:
Activin receptor type-1C, Activin receptor type IC, ACTR-IC, Activin receptor-like kinase 7, ALK-7, ACVR1C (HGNC:18123)
Target/Specificity:
This Activin A Receptor Type IC (ACVR1C) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-62 amino acids from the N-terminal region of human Activin A Receptor Type IC (ACVR1C).
Antigen Region:
33-62
Antigen Type: Synthetic Peptide
Gene Name: ACVR1C (HGNC:18123)
Gene ID: 130399
Primary Accession: Q8NER5
NCBI Accession: NP_001104501.1;NP_001104502.1;NP_001104503.1;NP_660302.2
Other Accession: Q8K348
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
ACVR1C, a serine/threonine protein kinase, is a type I receptor for the TGFB family of signaling molecules. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors. ACVR1C is a receptor for activin AB, activin B and NODAL. This protein plays a role in cell differentiation, growth arrest and apoptosis.
Other Names:
Activin receptor type-1C, Activin receptor type IC, ACTR-IC, Activin receptor-like kinase 7, ALK-7, ACVR1C (HGNC:18123)
Target/Specificity:
This Activin A Receptor Type IC (ACVR1C) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-62 amino acids from the N-terminal region of human Activin A Receptor Type IC (ACVR1C).
Antigen Region:
33-62
Antigen Type: Synthetic Peptide
Gene Name: ACVR1C (HGNC:18123)
Gene ID: 130399
Primary Accession: Q8NER5
NCBI Accession: NP_001104501.1;NP_001104502.1;NP_001104503.1;NP_660302.2
Other Accession: Q8K348
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
|---|
Write Your Own Review