ACTL6A polyclonal (N-term), anti-human
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In stock
SKU
AC-AP17002a
Catalog Number: AC-AP17002a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36747
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36747
Applications: WB
Datasheet
Request Information
Background:
This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.
Other Names:
Actin-like protein 6A, 53 kDa BRG1-associated factor A, Actin-related protein Baf53a, ArpNbeta, BRG1-associated factor 53A, BAF53A, INO80 complex subunit K, ACTL6A, BAF53, BAF53A, INO80K
Target/Specificity:
This ACTL6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-30 amino acids from the N-terminal region of human ACTL6A.
Antigen Region:
2-30
Antigen Type: Synthetic Peptide
Gene Name: ACTL6A
Gene ID: 86
Primary Accession: O96019
NCBI Accession: NP_004292.1;NP_817126.1;NP_829888.1
Other Accession: Q9Z2N8; Q4R333; NP_817126.1; NP_004292.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a family member of actin-related proteins (ARPs), which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a 53 kDa subunit protein of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. Together with beta-actin, it is required for maximal ATPase activity of BRG1, and for the association of the BAF complex with chromatin/matrix. Three transcript variants that encode two different protein isoforms have been described.
Other Names:
Actin-like protein 6A, 53 kDa BRG1-associated factor A, Actin-related protein Baf53a, ArpNbeta, BRG1-associated factor 53A, BAF53A, INO80 complex subunit K, ACTL6A, BAF53, BAF53A, INO80K
Target/Specificity:
This ACTL6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 2-30 amino acids from the N-terminal region of human ACTL6A.
Antigen Region:
2-30
Antigen Type: Synthetic Peptide
Gene Name: ACTL6A
Gene ID: 86
Primary Accession: O96019
NCBI Accession: NP_004292.1;NP_817126.1;NP_829888.1
Other Accession: Q9Z2N8; Q4R333; NP_817126.1; NP_004292.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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