ACTL7A polyclonal (N-term), anti-human
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In stock
SKU
AC-AP10469a
Catalog Number: AC-AP10469a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB22393
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB22393
Applications: WB
Datasheet
Request Information
Background:
ACTL7A is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. ACTL7A (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known.
Other Names:
Actin-like protein 7A, Actin-like-7-alpha, ACTL7A
Target/Specificity:
This ACTL7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-67 amino acids from the N-terminal region of human ACTL7A.
Antigen Region:
41-67
Antigen Type: Synthetic Peptide
Gene Name: ACTL7A
Gene ID: 10881
Primary Accession: Q9Y615
NCBI Accession: NP_006678.1
Other Accession: Q4R6Q3; NP_006678.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
ACTL7A is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. ACTL7A (ACTL7A), and related gene, ACTL7B, are intronless, and are located approximately 4 kb apart in a head-to-head orientation within the familial dysautonomia candidate region on 9q31. Based on mutational analysis of the ACTL7A gene in patients with this disorder, it was concluded that it is unlikely to be involved in the pathogenesis of dysautonomia. The ACTL7A gene is expressed in a wide variety of adult tissues, however, its exact function is not known.
Other Names:
Actin-like protein 7A, Actin-like-7-alpha, ACTL7A
Target/Specificity:
This ACTL7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-67 amino acids from the N-terminal region of human ACTL7A.
Antigen Region:
41-67
Antigen Type: Synthetic Peptide
Gene Name: ACTL7A
Gene ID: 10881
Primary Accession: Q9Y615
NCBI Accession: NP_006678.1
Other Accession: Q4R6Q3; NP_006678.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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