ACTR-IIA polyclonal, anti-human, mouse, rat, horse, dog, chicken, bovine, pig

Protein Family: Enzymes, Protein Kinases, Receptors and Channels

Pathway and Disease: Signaling Molecules and Interaction, Signal Transduction

Description:
Activin receptor type-2A (ACTR-IIA), on ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. ACTR-IIA is a receptor for activin A, activin B and inhibin A.

Alternate Names: Activin receptor type-2A, Activin receptor 2A, Activin receptor type IIA, ACTR-IIA, ACTRIIA, ACVR2A, ACVR2

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P27037

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ACTR-IIA.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.