ACTR-IIA Polyclonal Antibody

Background:
activin A receptor type 2A(ACVR2A) Homo sapiens This gene encodes a receptor that mediates the functions of activins, which are members of the transforming growth factor-beta (TGF-beta) superfamily involved in diverse biological processes. The encoded protein is a transmembrane serine-threonine kinase receptor which mediates signaling by forming heterodimeric complexes with various combinations of type I and type II receptors and ligands in a cell-specific manner. The encoded type II receptor is primarily involved in ligand-binding and includes an extracellular ligand-binding domain, a transmembrane domain and a cytoplasmic serine-threonine kinase domain. This gene may be associated with susceptibility to preeclampsia, a pregnancy-related disease which can result in maternal and fetal morbidity and mortality. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jun 2013],

Alternative Names:
ACVR2A, ACVR2, Activin receptor type-2A, Activin receptor type IIA, ACTR-IIA, ACTRIIA

Immunogen: The antiserum was produced against synthesized peptide derived from human ACTR-IIA. AA range:10-59

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 48

GeneID: ACVR2A

Storage: -20°C/1 year

NOTE: For Research Use Only