ACVR1B polyclonal, anti-human, mouse

Background:
This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.

Synonyms: ACTRIB, ACVRLK4, ALK4, SKR2

Cellular Location: Cell membrane Single-pass type I membrane protein

Immunogen:
Recombinant protein of human ACVR1B

Gene Symbol: ACVR1B

Gene ID: 91

Swiss prot: P36896

Calculated MW: 57kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.