ACVR1B Polyclonal Antibody

Background:
This gene encodes an activin A type IB receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. This protein is a type I receptor which is essential for signaling. Mutations in this gene are associated with pituitary tumors. Alternate splicing results in multiple transcript variants.

Research Area: Cancer, Signal Transduction, Stem Cells

Synonyms:
ACVR1B, ACTRIB, ACVRLK4, ALK4, SKR2

Immunogen: Recombinant fusion protein of human ACVR1B (NP_004293.1).

Swissprot: P36896
Gene ID: 91

Calculated MW: 51 kDa/53 kDa/54 kDa/56 kDa/61 kDa
Observed MW: 49 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.