ACVR1C polyclonal, anti-human, mouse, rat

Background:
ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).

Synonyms: ACVRLK7, ALK7

Cellular Location: Membrane Single-pass type I membrane protein

Immunogen:
Recombinant protein of human ACVR1C

Gene Symbol: ACVR1C

Gene ID: 130399

Swiss prot: Q8NER5

Calculated MW: 55kDa

Recommended dilution:
WB 1:500-2000, IHC 1:100-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.