ACVR1C Polyclonal Antibody

Background:
ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms:
ACVR1C, ACVRLK7, ALK7

Immunogen: Recombinant fusion protein of human ACVR1C (NP_660302.2).

Swissprot: Q8NER5
Gene ID: 130399

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IHC 1:100-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.