ACVRL1 polyclonal (N-term), anti-human

ACVRL1 polyclonal (N-term), anti-human

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In stock
SKU
AC-AP20564a
Catalog Number: AC-AP20564a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB47704
Applications: IHC-P, WB
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Background:
Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.

Other Names:
Serine/threonine-protein kinase receptor R3, SKR3, Activin receptor-like kinase 1, ALK-1, TGF-B superfamily receptor type I, TSR-I, ACVRL1, ACVRLK1, ALK1

Target/Specificity:
This ACVRL1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 11-44amino acids from the N-terminal region of human ACVRL1.

Antigen Type: Synthetic Peptide

Gene Name: ACVRL1
Gene ID: 94
Primary Accession: P37023
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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