ACY1 antibody (clone 4F1-B7), anti-human

Background:
Aminoacylase-1 is a cytosolic, homodimeric, zinc-binding enzyme that catalyzes the hydrolysis of acylated L-amino acids to L-amino acids and acyl group, and has been postulated to function in the catabolism and salvage of acylated amino acids. ACY1 has been assigned to chromosome 3p21.1, a region reduced to homozygosity in small-cell lung cancer (SCLC), and its expression has been reported to be reduced or undetectable in SCLC cell lines and tumors. The amino acid sequence of human aminoacylase-1 is highly homologous to the porcine counterpart, and ACY1 is the first member of a new family of zinc-binding enzymes.

Other Names:
Aminoacylase-1, ACY-1, N-acyl-L-amino-acid amidohydrolase, ACY1

Antigen Type:
Recombinant Protein

Gene Name: ACY1
Gene ID: 95
NCBI Accession: NP_000657.1;NP_001185824.1;NP_001185825.1;NP_001185826.1;NP_001185827.1
Primary Accession: Q03154
Other Accession: BC000545
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .