ADA polyclonal antibody, anti-human, mouse, rat

Background:
This gene encodes an enzyme that catalyzes the hydrolysis of adenosine to inosine. Various mutations have been described for this gene and have been linked to human diseases. Deficiency in this enzyme causes a form of severe combined immunodeficiency disease (SCID)| in which there is dysfunction of both B and T lymphocytes with impaired cellular immunity and decreased production of immunoglobulins| whereas elevated levels of this enzyme have been associated with congenital hemolytic anemia.

Research Area: Cancer, Epigenetics and nuclear signaling, Metabolism

Synonyms: Adenosine deaminase , EC 3.5.4.4, Adenosine aminohydrolase

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year