ADA19 polyclonal antibody, anti-human, mouse

Background:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions| including fertilization| muscle development| and neurogenesis. This member is a type I transmembrane protein and serves as a marker for dendritic cell differentiation. It has been demonstrated to be an active metalloproteinase| which may be involved in normal physiological processes such as cell migration| cell adhesion| cell-cell and cell-matrix interactions| and signal transduction. It is proposed to play a role in pathological processes| such as cancer| inflammatory diseases| renal diseases| and Alzheimer's disease.

Research Area: Signal transduction, Cancer, Cell biology

Synonyms: Disintegrin and metalloproteinase domain-containing protein 19 , ADAM 19, EC 3.4.24.-, Meltrin-beta, Metalloprotease and disintegrin dendritic antigen marker, MADDAM

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year