ADAM11 Polyclonal Antibody

Background:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene represents a candidate tumor supressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping.

Research Area: Cancer, Cell Biology, Signal Transduction

Synonyms:
A disintegrin and metalloproteinase domain 11, ADA11, ADAM 11, Adam11, and cysteine-rich protein, Disintegrin and metalloproteinase domain-containing protein 11, disintegrin-like, MDC, Metalloproteinase like, disintegrin like, and cysteine rich protein, Metalloproteinase-like

Immunogen: Synthetic peptide of human ADAM11

Swissprot: O75078
Gene Accession: NP_002381

Calculated MW: 83 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:200-1:1000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-15505/sc-15507