ADAM17 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway.

Synonyms: CSVP, TACE, NISBD, ADAM18, CD156B

Cellular Location: Cytoplasm

Immunogen:
Recombinant protein of human ADAM17

Gene Symbol: ADAM17

Gene ID: 6868

Swiss prot: P78536

Calculated MW: 93kDa

Recommended dilution:
IHC 1:10-50

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.