ADAM17 polyclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AP1492a
Catalog Number: AC-AP1492a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB13805
Applications: FC, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB13805
Applications: FC, WB
Datasheet
Request Information
Background:
ADAM17 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM17 functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway.
Other Names:
Disintegrin and metalloproteinase domain-containing protein 17, ADAM 17, Snake venom-like protease, TNF-alpha convertase, TNF-alpha-converting enzyme, CD156b, ADAM17, CSVP, TACE
Target/Specificity:
This ADAM17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-224 amino acids of human ADAM17.
Antigen Region:
195-224
Antigen Type: Synthetic Peptide
Gene Name: ADAM17 (HGNC:195)
Gene ID: 6868
Primary Accession: P78536
NCBI Accession: NP_003174.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
ADAM17 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM17 functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway.
Other Names:
Disintegrin and metalloproteinase domain-containing protein 17, ADAM 17, Snake venom-like protease, TNF-alpha convertase, TNF-alpha-converting enzyme, CD156b, ADAM17, CSVP, TACE
Target/Specificity:
This ADAM17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-224 amino acids of human ADAM17.
Antigen Region:
195-224
Antigen Type: Synthetic Peptide
Gene Name: ADAM17 (HGNC:195)
Gene ID: 6868
Primary Accession: P78536
NCBI Accession: NP_003174.3
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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