ADAM17 / TACE polyclonal, anti-human

Background:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway.

Other Names:
Disintegrin and metalloproteinase domain-containing protein 17, ADAM 17, 3.4.24.86, Snake venom-like protease, TNF-alpha convertase, TNF-alpha-converting enzyme, CD156b, ADAM17, CSVP, TACE

Antigen Types:
Synthetic Peptide

Gene Name:
ADAM17 (HGNC:195)
Gene ID:
6868
Primary Accession: P78536
Other Accession: NP_003174;6868;11491 (mouse);