ADAM8 polyclonal antibody, anti-human, mouse, rat

Background:
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins| and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions| including fertilization| muscle development| and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration| and it is thought to be a target for allergic respiratory diseases| including asthma. Alternative splicing results in multiple transcript variants.

Research Area: Signal transduction, Cancer, Cell biology

Synonyms: Disintegrin and metalloproteinase domain-containing protein 8 , ADAM 8, EC 3.4.24.-, Cell surface antigen MS2, CD antigen CD156a

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year