ADAMTS-1 polyclonal antibody, anti-human

Background:
ADAMTS1 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. ADAM metallopeptidase with thrombospondin type 1 motif 1 encoded by ADAMTS1 contains two disintegrin loops and three C-terminal TS motifs and has anti-angiogenic activity. The expression of ADAMTS1 may be associated with various inflammatory processes as well as development of cancer cachexia. ADAMTS1 is likely to be necessary for normal growth, fertility, and organ morphology and function.

Research Area: Cardiovascular, Tags & Cell Markers

Synonyms: ADAMTS1, KIAA1346, METH1, A disintegrin and metalloproteinase with thrombospondin motifs 1, ADAM-TS 1, ADAM-TS1, ADAMTS-1, METH-1

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year