ADAMTS-2 Polyclonal Antibody

Background:
ADAM metallopeptidase with thrombospondin type 1 motif 2(ADAMTS2) Homo sapiens This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature procollagen N-proteinase. This proteinase excises the N-propeptide of the fibrillar procollagens types I-III and type V. Mutations in this gene cause Ehlers-Danlos syndrome type VIIC, a recessively inherited connective-tissue disorder. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically

Alternative Names:
ADAMTS2, PCINP, PCPNI, A disintegrin and metalloproteinase with thrombospondin motifs 2, ADAM-TS 2, ADAM-TS2, ADAMTS-2, Procollagen I N-proteinase, PC I-NP, Procollagen I/II amino propeptide-processin

Immunogen: Synthesized peptide derived from ADAMTS-2 . at AA range: 1140-1220

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 100

GeneID: ADAMTS2

Storage: -20°C/1 year

NOTE: For Research Use Only