ADAMTS18 Polyclonal Antibody

Background:
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene has a high sequence similarity to the protein encoded by gene ADAMTS16, another family member. It is thought to function as a tumor suppressor. Alternatively spliced transcript variants have been identified, but their biological validity has not been determined.

Research Area: Cancer, Cell Biology, Signal Transduction

Synonyms:
A disintegrin and metalloproteinase with thrombospondin motifs 18, A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 18, A disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif 21, ADAM metallopeptidase with thrombospondin type 1 motif 18, ADAM-TS 18, ADAM-TS18, ADAMTS 18, ADAMTS-18, ADAMTS18, ADAMTS21, ATS18, Disintegrin and metalloprotease like protein, EC 3.4.24., KNO2

Immunogen: Recombinant protein of human ADAMTS18

Swissprot: Q8TE60
Gene Accession: BC063283

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-67706/sc-67707/sc-68416