ADAMTS2 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
ADAMTS2, A disintegrin and metalloproteinase with thrombospondin motifs 2, also known as procollagen I N-proteinase(PC I-NP), is an enzyme that in humans is encoded by the ADAMTS2 gene. The ADAMTS2 gene contains 22 exons. The human ADAMTS2 gene is mapped to chromosome 5q23-q24 by analysis of somatic cell hybrids. ADAMTS2 is responsible for processing several types of procollagen proteins. Procollagens are the precursors of collagens, the proteins that add strength and support to many body tissues. Specifically, this enzyme clips a short chain of amino acids off one end of the procollagen. This clipping step is necessary for collagen molecules to function normally and assemble into fibrils outside cells.

Description:
Rabbit IgG polyclonal antibody for A disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAMTS2) detection. Tested with WB, IHC-P, IHC-F in Human, Mouse, Rat.

Synonyms:
A disintegrin and metalloproteinase with thrombospondin motifs 2 antibody, A disintegrin like and metalloprotease(reprolysin type) with thrombospondin type 1 motif 2 antibody, ADAM metallopeptidase with thrombospondin type 1 motif 2 antibody, ADAM TS 2 antibody, ADAM TS2 antibody, ADAM-TS 2 antibody, ADAM-TS2 antibody, ADAMTS 3 antibody, ADAMTS-2 antibody, ADAMTS2 antibody, ATS2_HUMAN antibody, EC 3.4.24.14 antibody, EDS VIIB antibody, EDS VIIC antibody, hPCPNI antibody, NPI antibody, PC I NP antibody, PC I-NP antibody, PCINP antibody, PCPNI antibody, pNPI antibody, Procollagen I N proteinase antibody, Procollagen I N-proteinase antibody, Procollagen I/II amino propeptide processing enzyme antibody, Procollagen I/II amino propeptide-processing enzyme antibody, Procollagen N endopeptidase antibody, Procollagen N-endopeptidase antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human ADAMTS2(1189-1204aa KTRNQRIQELIDEMRK), different from the related rat and mouse sequences by three amino acids.A synthetic peptide corresponding to a sequence at the C-terminus of human ADAMTS2(1189-1204aa KTRNQRIQELIDEMRK), different from the related rat and mouse sequences by three amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat.
Predicted to work with: mouse.

Applications: WB, IHC-P, IHC-F

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.