ADCK3 Polyclonal Antibody
€0.00
In stock
SKU
E-AB-67859
Catalog Number: E-AB-67859
Isotype: Rabbit IgG
Reactivity: human, mouse, rat
Applications: WB,IHC
Datasheet, Questions? Contact us!
Isotype: Rabbit IgG
Reactivity: human, mouse, rat
Applications: WB,IHC
Datasheet, Questions? Contact us!
Background:
This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined.
Research Area: Cancer, Metabolism, Signal Transduction
Synonyms:
COQ8A, ADCK3, ARCA2, CABC1, COQ10D4, COQ8, SCAR9
Immunogen: Recombinant fusion protein of human ADCK3 (NP_064632.2).
Swissprot: Q8NI60
Gene ID: 56997
Calculated MW: 18 kDa/42 kDa/66 kDa/71 kDa
Observed MW: 55 kDa
Purification Method: Affinity purification
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200"
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
This gene encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found; however, their full-length nature has not been determined.
Research Area: Cancer, Metabolism, Signal Transduction
Synonyms:
COQ8A, ADCK3, ARCA2, CABC1, COQ10D4, COQ8, SCAR9
Immunogen: Recombinant fusion protein of human ADCK3 (NP_064632.2).
Swissprot: Q8NI60
Gene ID: 56997
Calculated MW: 18 kDa/42 kDa/66 kDa/71 kDa
Observed MW: 55 kDa
Purification Method: Affinity purification
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200"
Storage:
Store at -20°C. Avoid freeze / thaw cycles.
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