ADCY5/6 rabbit polyclonal, anti-human, mouse, rat

Backgroud: ADCY5 encodes a member (adenylate cyclase 5) of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for ADCY5.

Synonyms: ADCY5, Adenylate cyclase type 5, ATP pyrophosphate-lyase 5, Adenylate cyclase type V, Adenylyl cyclase 5, ADCY6, KIAA0422, Adenylate cyclase type 6, ATP pyrophosphate-lyase 6, Adenylate cyclase type VI, Adenylyl cyclase 6, Ca(2+)-inhibitabl

Gene Name: ADCY5/ADCY6

Gene ID: 111/112

SwissProt ID: O95622/O43306

Purification: Affinity Chromatography

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.