ADCY5 Polyclonal Antibody

Background:
This gene encodes a member of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for this gene.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
AC 5, AC5, ADCY 5, Adcy5, ADCY5, Adenylate cyclase type 5, Adenylate cyclase type V, Adenylyl cyclase 5, ATP pyrophosphate lyase 5, ATP pyrophosphate-lyase 5

Immunogen: Synthetic peptide of human ADCY5

Swissprot: O95622
Gene Accession: NP_001186571

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-74299/sc-74300/sc-74301/sc-590