ADD1 antibody (clone 2C9), anti-human
€435.00
In stock
SKU
AC-AT1053a
Catalog Number: AC-AT1053a
Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IHC, E
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Size: 100 µg
Isotype: mouse IgG1 kappa
Applications: WB, IHC, E
Request Information AC-AT1053a">Request Information
Background:
Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
Other Names:
Alpha-adducin, Erythrocyte adducin subunit alpha, ADD1, ADDA
Antigen Type:
Recombinant Protein
Gene Name: ADD1
Gene ID: 118
NCBI Accession: NP_001110.2;NP_054908.2;NP_054909.2;NP_789771.1
Primary Accession: P35611
Other Accession: BC042998
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.
Other Names:
Alpha-adducin, Erythrocyte adducin subunit alpha, ADD1, ADDA
Antigen Type:
Recombinant Protein
Gene Name: ADD1
Gene ID: 118
NCBI Accession: NP_001110.2;NP_054908.2;NP_054909.2;NP_789771.1
Primary Accession: P35611
Other Accession: BC042998
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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