ADD1 (S726) polyclonal, anti-human, mouse, rat

Bio Backgrounds:
Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms; however, not all variants have been fully described.

Other Names:
Alpha-adducin, Erythrocyte adducin subunit alpha, ADD1, ADDA

Target/Specificity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Gene Name:
ADD1
Gene ID:
118
NCBI Accession:
NP_001110.2;NP_054908.2;NP_054909.2;NP_789771.1
Primary Accession: P35611

Format: affinity Purified IgG, in PBS, 0.02% sodium azide and 50% glycerol.