ADGRE3 Polyclonal Antibody

Background:
This gene encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing results in multiple transcript variants encoding different isoforms.

Research Area: Immunology, Signal transduction

Synonyms:
Egf like module containing mucin like hormone receptor like 3, Egf like module containing mucin like receptor 3, EGF like module containing mucin like receptor EMR3, EMR 3

Immunogen: Synthetic peptide of human ADGRE3

Swissprot: Q9BY15
Gene Accession: NP115960

Calculated MW: 73 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.96 mg/mL
Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.