ADH5 polyclonal (Center), anti-human

ADH5 polyclonal (Center), anti-human

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In stock
SKU
AC-AP8562C
Catalog Number: AC-AP8562C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB22372
Applications: FC, IHC-P, WB
Datasheet

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Background:
ADH5 is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis.

Other Names:
Alcohol dehydrogenase class-3, Alcohol dehydrogenase 5, Alcohol dehydrogenase class chi chain, Alcohol dehydrogenase class-III, Glutathione-dependent formaldehyde dehydrogenase, FALDH, FDH, GSH-FDH, 111-, S-(hydroxymethyl)glutathione dehydrogenase, ADH5 (HGNC:253), ADHX, FDH

Target/Specificity:
This ADH5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 212-239 amino acids from the Central region of human ADH5.

Antigen Region:
212-239

Antigen Type: Synthetic Peptide

Gene Name: ADH5 (HGNC:253)
Gene ID: 128
Primary Accession: P11766
NCBI Accession: NP_000662.3
Other Accession: O19053
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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