ADHX polyclonal antibody, anti-human, mouse, rat

Background:
This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates| including ethanol| retinol| other aliphatic alcohols| hydroxysteroids| and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation| but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione| a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde| a potent irritant and sensitizing agent that causes lacrymation| rhinitis| pharyngitis| and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene.

Research Area: Signal transduction, Metabolism

Synonyms: Alcohol dehydrogenase class-3 , EC 1.1.1.1, Alcohol dehydrogenase 5, Alcohol dehydrogenase class chi chain, Alcohol dehydrogenase class-III, Glutathione-dependent formaldehyde dehydrogenase, FALDH

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year