Adiponectin (ADPN) polyclonal, anti-human

Adiponectin (ADPN) polyclonal, anti-human

€265.00
In stock
SKU
IMD-11010
Catalog Number: IMD-11010
Size: 0,1 mg
Applications: WB, ELISA
Datasheet
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Polyclonal Antibody against Human Adiponectin

Application: ELISA, WB

Host: Rabbit

INTRODUCTION
Adiponectin, also termed gelatin-binding protein-28 (GBP28), AdipoQ, ACP30 (Acrp30), or apM, is a major adipocyte-secreted adipokine which is abundantly present in the circulation as three distinct oligomeric complexes: LMW(67kDa), MMW(167kDa) and HMW(300kDa) adiponectin. Its levels are decreased in insulin resistance, diabetes and cardiovascular disease. Conversely, elevation of circulating adiponectin concentrations can alleviate various vascular dysfunctions in animal models, suggesting this adipokine exerts vasculo-protective effects. In addition, adiponectin may also be of importance in the development and progression of several malignancies.

PURIFICATION: Rabbit crude IgG was purified by protein-G chromatography.

IMMUNOGEN: Recombinant full-length human adiponectin expressed in mammalian cells.

SPECIFICITY: The antibody detects three types of circular human adiponectin and monomer (30kDa) adiponectin.

FORMULATION: Liquid in phosphate-buffered saline (PBS).

STORAGE
Store at –20°C for less than one week. For long-term STORAGE: , aliquot and freeze at -70°C. Avoid repeated freeze/defrost cycles.

APPLICATION/ USAGE
Western blot - This antibody can be used at 0.1-0.2 μg/mL with the appropriate secondary reagents to detect human adiponectin.
ELISA - This antibody can be used at 0.5-1.0 μg/mL with the appropriate secondary reagents to detect human adiponectin.
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