Adiponectin polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
ADIPOQ(Adipocyte-, C1q-, and Collagen Domain-Containing), also known as APM1, ADPN or ACDC, is a protein which in humans is encoded by the ADIPOQ gene. Using FISH, Das et al.(2001) mapped the mouse Acrp30 gene to chromosome 16 in a region showing homology of synteny with human 3q27. By RNase protection and Western blot analysis, Schaffler et al.(1999) showed that APM1 is expressed by differentiated adipocytes as a 33-kD protein that is also detectable in serum. By sequence comparisons, they found links between APM1 and TNF family ligands as well as to cytokines expressed by T cells. Adiponectin is a protein hormone that modulates a number of metabolic processes, including glucose regulation and fatty acid oxidation. Adiponectin is exclusively secreted from adipose tissue(and also from the placenta in pregnancy) into the bloodstream and is very abundant in plasma relative to many hormones.

Description:
Rabbit IgG polyclonal antibody for Adiponectin (ADIPOQ) detection. Tested with WB, IHC-P, IHC-F, ELISA in Human, Mouse, Rat.

Synonyms:
30 kDa adipocyte complement related protein antibody, 30 kDa adipocyte complement-related protein antibody, ACDC antibody, ACRP 30 antibody, ACRP30 antibody, ADIPO_HUMAN antibody, Adipocyte antibody, Adipocyte C1q and collagen domain containing protein antibody, Adipocyte complement related 30 kDa protein antibody, Adipocyte complement related protein of 30 kDa antibody, Adipocyte complement-related 30 kDa protein antibody, Adiponectin antibody, AdipoQ antibody, Adipose most abundant gene transcript 1 antibody, Adipose most abundant gene transcript 1 protein antibody, Adipose specific collagen like factor antibody, ADIPQTL1 antibody, ADPN antibody, APM 1 antibody, apM-1 antibody, ApM1 antibody, C1q and collagen domain-containing protein antibody, GBP 28 antibody, GBP28 antibody, Gelatin binding protein antibody, Gelatin binding protein 28 antibody, Gelatin-binding protein antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human ADIPOQ(224-244aa LYADNDNDSTFTGFLLYHDTN), different from the related mouse and rat sequences by one amino acid.

Form: Lyophilized; Each vial contains 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P, IHC-F, ELISA

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.