ADK polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP7091b
Catalog Number: AC-AP7091b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB05395
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB05395
Applications: IHC-P, WB
Datasheet
Request Information
Background:
Adenosine kinase is an abundant enzyme in mammalian tissues. The enzyme catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Alternative splicing results in two transcript variants encoding different isoforms. Both isoforms of the enzyme phosphorylate adenosine with identical kinetics and both require Mg2+ for activity.
Other Names:
Adenosine kinase, AK, Adenosine 5'-phosphotransferase, ADK
Target/Specificity:
This ADK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-352 amino acids from the C-terminal region of human ADK.
Antigen Region:
322-352
Antigen Type: Synthetic Peptide
Gene Name: ADK (HGNC:257)
Gene ID: 132
Primary Accession: P55263
NCBI Accession: NP_001114.2;NP_001189378.1;NP_001189379.1;NP_006712.2
Other Accession: NP_006712
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Adenosine kinase is an abundant enzyme in mammalian tissues. The enzyme catalyzes the transfer of the gamma-phosphate from ATP to adenosine, thereby serving as a regulator of concentrations of both extracellular adenosine and intracellular adenine nucleotides. Adenosine has widespread effects on the cardiovascular, nervous, respiratory, and immune systems and inhibitors of the enzyme could play an important pharmacological role in increasing intravascular adenosine concentrations and acting as anti-inflammatory agents. Alternative splicing results in two transcript variants encoding different isoforms. Both isoforms of the enzyme phosphorylate adenosine with identical kinetics and both require Mg2+ for activity.
Other Names:
Adenosine kinase, AK, Adenosine 5'-phosphotransferase, ADK
Target/Specificity:
This ADK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 322-352 amino acids from the C-terminal region of human ADK.
Antigen Region:
322-352
Antigen Type: Synthetic Peptide
Gene Name: ADK (HGNC:257)
Gene ID: 132
Primary Accession: P55263
NCBI Accession: NP_001114.2;NP_001189378.1;NP_001189379.1;NP_006712.2
Other Accession: NP_006712
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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