ADRA1A Polyclonal Antibody

Background:
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties.

Research Area: Cancer, Cardiovascular, Neuroscience, Signal Transduction

Synonyms:
ADRA1A, ADRA1C, ADRA1L1, ALPHA1AAR

Immunogen: Recombinant fusion protein of human ADRA1A (NP_150646.3).

Swissprot: P35348
Gene ID: 148

Calculated MW: 32-52 kDa
Observed MW: 51 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.