ADRA1B Polyclonal Antibody

Background:
Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1B-adrenergic receptor, which induces neoplastic transformation when transfected into NIH 3T3 fibroblasts and other cell lines. Thus, this normal cellular gene is identified as a protooncogene. This gene comprises 2 exons and a single large intron of at least 20 kb that interrupts the coding region.

Research Area: Cancer, Neuroscience

Synonyms:
ADA1B, ADRA 1, Adra 1b, ADRA1, ADRA1B, Adrenergic alpha 1B receptor, Adrenergic receptor alpha 1b, Adrenoceptor alpha 1B, Alpha 1 adrenergic receptor, Alpha 1B adrenoceptor, Alpha 1B adrenoreceptor, Alpha-1B adrenergic receptor, Alpha-1B adrenoceptor, Alpha-1B adrenoreceptor, Alpha1 adrenergic receptor, Alpha1B adrenergic receptor, Alpha1BAR

Immunogen: Synthetic peptide of human ADRA1B

Swissprot: P35368
Gene Accession: NP_000670

Calculated MW: 57 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: WB 1:500-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-27136/sc-1476