ADRA2C polyclonal (C-term), anti-human
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In stock
SKU
AC-AP14582B
Catalog Number: AC-AP14582B
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34564
Applications: WB, IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34564
Applications: WB, IHC-P
Datasheet
Request Information
Background:
Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the centralnervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences.
Other Names:
Alpha-2C adrenergic receptor, Alpha-2 adrenergic receptor subtype C4, Alpha-2C adrenoreceptor, Alpha-2C adrenoceptor, Alpha-2CAR, ADRA2C, ADRA2L2, ADRA2RL2
Target/Specificity:
This ADRA2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 354-382 amino acids from the C-terminal region of human ADRA2C.
Antigen Region:
354-382
Antigen Type: Synthetic Peptide
Gene Name: ADRA2C
Gene ID: 152
Primary Accession: P18825
NCBI Accession: NP_000674.2
Other Accession: P22086; Q01337; NP_000674.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the centralnervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences.
Other Names:
Alpha-2C adrenergic receptor, Alpha-2 adrenergic receptor subtype C4, Alpha-2C adrenoreceptor, Alpha-2C adrenoceptor, Alpha-2CAR, ADRA2C, ADRA2L2, ADRA2RL2
Target/Specificity:
This ADRA2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 354-382 amino acids from the C-terminal region of human ADRA2C.
Antigen Region:
354-382
Antigen Type: Synthetic Peptide
Gene Name: ADRA2C
Gene ID: 152
Primary Accession: P18825
NCBI Accession: NP_000674.2
Other Accession: P22086; Q01337; NP_000674.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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