ADRB2 Polyclonal Antibody

Background:
This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity and type 2 diabetes.

Research Area: Cancer, Cardiovascular, Signal Transduction

Synonyms:
ADRB2, ADRB2, ADRB2R, ADRBR, Adrenergic beta 2 receptor surface, Adrenoceptor beta 2 surface, B2AR, BAR, beta 2 adrenoceptor, Beta 2 adrenoreceptor, Beta-2 adrenergic receptor, Beta-2 adrenoceptor, Beta-2 adrenoreceptor, BETA2AR, Catecholamine receptor, OTTHUMP00000160386

Immunogen: Synthetic peptide of human ADRB2

Swissprot: P07550
Gene Accession: NP_000015

Calculated MW: 46 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:1000-1:2000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-9042/sc-569/sc-570