AEBP1 polyclonal, anti-human, mouse, rat, pig, bovine

Protein Family: Translation Factors, Transcription Factors, Protein Kinases, Enzymes

Pathway and Disease: Immune System, Signaling Molecules and Interaction, Transcription, Translation

Description:
Adipocyte enhancer-binding protein 1 (AEBP1) up-regulates MAP-kinase activity leading to enhanced proliferation and reduced differentiation of the adipocyte. AEBP1 also up-regulates NF-kappa-B activity in macrophages via phosphorylation and subsequent degradation of I-kappa-B-alpha. This leads to enhanced macrophage inflammatory responsiveness. It can also act as a transcriptional repressor.

Alternate Names: AEBP1, ACLP, AE-binding protein 1, Aortic carboxypeptidase-like protein, Adipocyte enhancer-binding protein 1

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: Q14113

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human AEBP1.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.