AF/LE Purified Anti-Mouse CD183/CXCR3 Antibody [clone CXCR3-173]
€0.00
In stock
SKU
E-AB-F11140
Catalog Number: E-AB-F11140
Reactivity: Mouse, Clone: CXCR3-173
Isotype: Armenian Hamster IgG, Conjugation: None (Purified antibody-Azide Free/Low endotoxin)
Applications: FCM,Block
Datasheet, Questions? Contact us!
Reactivity: Mouse, Clone: CXCR3-173
Isotype: Armenian Hamster IgG, Conjugation: None (Purified antibody-Azide Free/Low endotoxin)
Applications: FCM,Block
Datasheet, Questions? Contact us!
Background:
CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.
Research Area: Cancer, Cardiovascular, Immunology, Signal transduction
Synonyms:
C-X-C chemokine receptor type 3, Cxcr3, CXC-R3, CXCR-3, Interferon-inducible protein 10 receptor, IP-10 receptor, CD183/CXCR3
Swissprot: O88410
Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Concentration: 0.5 mg/mL
Storage:
Store at 2~8°C. Do not freeze.
Alternative for product with catalog number:
126526, 126537
CD183/CXCR3, also known as CXCR3, is a member of the C-X-C chemokine family, characterized by a pair of cysteine residues separated by a single amino acid. CXCR3 is a 38 kD seven pass transmembrane receptor coupled to G-protein. It mediates Ca2+ mobilization and chemotaxis in response to C-X-C chemokines, such as IP10 (CXCL10), MIG (CXCL9), I-TAC (CXCL11) and PF4 (CXCL4). CXCR3 is expressed primarily on activiated T lymphocytes, NK cells, and some epithelial cells and endothelial cells. It is not expressed on B cells, monocytes or granulocytes.
Research Area: Cancer, Cardiovascular, Immunology, Signal transduction
Synonyms:
C-X-C chemokine receptor type 3, Cxcr3, CXC-R3, CXCR-3, Interferon-inducible protein 10 receptor, IP-10 receptor, CD183/CXCR3
Swissprot: O88410
Buffer: 0.2 μm filtered in PBS, pH7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or preservatives. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Concentration: 0.5 mg/mL
Storage:
Store at 2~8°C. Do not freeze.
Alternative for product with catalog number:
126526, 126537
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