AF1Q antibody (clone 2A9-1B7), anti-human
€435.00
In stock
SKU
AC-AT1064a
Catalog Number: AC-AT1064a
Size: 100 µg
Isotype: mouse IgG2a kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2a kappa
Applications: WB, E
Request Information AC-AT1064a">Request Information
Background:
The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1;11)(q21;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested.
Other Names:
Protein AF1q, MLLT11, AF1Q
Antigen Type:
Recombinant Protein
Gene Name: MLLT11
Gene ID: 10962
NCBI Accession: NP_006809.1
Primary Accession: Q13015
Other Accession: BC009624
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
The gene variously symbolized ALL1, HRX, or MLL located on 11q23 has been demonstrated to be fused with a number of translocation partners in cases of leukemia. t(1;11)(q21;q23) translocations that fused the MLL gene to a gene on chromosomal band 1q21 in 2 infants with acute myelomonocytic leukemia have been demonstrated. The N-terminal portion of the MLL gene is critical for leukemogenesis in translocations involving band 11q23. This gene encodes 90 amino acids. It was found to be highly expressed in the thymus but not in peripheral lymphoid tissues. In contrast to its restricted distribution in normal hematopoietic tissue, this gene was expressed in all leukemic cell lines tested.
Other Names:
Protein AF1q, MLLT11, AF1Q
Antigen Type:
Recombinant Protein
Gene Name: MLLT11
Gene ID: 10962
NCBI Accession: NP_006809.1
Primary Accession: Q13015
Other Accession: BC009624
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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